The question of whether you should make theme adjustments is always a difficult one to answer.  It is even be harder to do and not negatively affect your onsite readers.  That being said here are my thoughts.

Limit major theme changes to no more than once a month.  Anymore than once a month clearly defines [...]

I am in no way an expert in Blogger or BlogSpot, but I am passing along to your a nice free article on how to write a theme there since I know some of you blog there.
How To Create A Blogger/Blogspot Theme by Brad
This tutorial will cover the steps needed to create your own blogger [...]

The First thing you need to do when thinking about a theme is deciding who you are designing it for.  There are a number of tools that will tell you what your visitor’s monitors resolution is set to and this is a key factor to consider.  As often as not these days new computers [...]

The first thing you notice about any blog is the theme.  If you have played with as many of them as I have you start to recognize where they came from too.  Most of them I see unfortunately come from stock sites leaving very little in the way of personalization.  I run one basic design, [...]

Since I have already been asked twice why I am still using the WordPress Default theme, I suppose I should be answering that question.  I Don’t have one yet.  Since the concept for this blog is less than 2 days old and the gerbil that turns the wheel inside my head was taking his turn [...]

WordPress 2.5 seems to be more particular than early releases to coding errors.  One possible result is the loss of sidebars and footers.  Elezend asked about this very problem on Lorelle on Wordpress, then again at Brad’s Tiny World.  Elezend’s footer which contains MyBlogLog and Blog Catalog displays just up and disappeared upon upgrading.  Personally [...]